Continuous flow photolysis of aryl azides: Preparation of 3H-azepinones.

ABSTRACT: Photolysis of aryl azides to give nitrenes, and their subsequent rearrangement in the presence of water to give 3H-azepinones, is performed in continuous flow in a photoreactor constructed of fluorinated ethylene polymer (FEP) tubing. Fine tuning of the reaction conditions using the flow reactor allowed minimization of secondary photochemical reactions.

SUBMITTER: Bou-Hamdan FR 

PROVIDER: S-EPMC3167900 | biostudies-literature | 2011

REPOSITORIES: biostudies-literature