Microbial community and metabolomic comparison of irritable bowel syndrome faeces.

ABSTRACT: Human health relies on the composition of microbiota in an individual's gut and the synthesized metabolites that may alter the gut environment. Gut microbiota and faecal metabolites are involved in several gastrointestinal diseases. In this study, 16S rRNA-specific denaturing gradient gel electrophoresis and quantitative PCR analysis showed that the mean similarity of total bacteria was significantly different (P<0.001) in faecal samples from patients with irritable bowel syndrome (IBS; n = 11) and from non-IBS (nIBS) patients (n = 8). IBS subjects had a significantly higher diversity of total bacteria, as measured by the Shannon index (H') (3.36

SUBMITTER: Ponnusamy K 

PROVIDER: S-EPMC3167923 | biostudies-literature | 2011 Jun

REPOSITORIES: biostudies-literature