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One-pot four-component synthesis of pyrimidyl and pyrazolyl substituted azulenes by glyoxylation-decarbonylative alkynylation-cyclocondensation sequences.

ABSTRACT: A novel one-pot four-component synthesis of pyrimidyl- and pyrazolylazulenes through the use of glyoxylation-decarbonylative alkynylation-cyclocondensation sequences starting from azulene or guaiazulene as substrates, gives rise to the formation of the target compounds in moderate to good yields.

SUBMITTER: Gers CF

PROVIDER: S-EPMC3168959 | biostudies-literature | 2011

REPOSITORIES: biostudies-literature

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One-pot four-component synthesis of pyrimidyl and pyrazolyl substituted azulenes by glyoxylation-decarbonylative alkynylation-cyclocondensation sequences.

Gers Charlotte F CF Rosellen Julia J Merkul Eugen E Müller Thomas J J TJ

Beilstein journal of organic chemistry 20110826

A novel one-pot four-component synthesis of pyrimidyl- and pyrazolylazulenes through the use of glyoxylation-decarbonylative alkynylation-cyclocondensation sequences starting from azulene or guaiazulene as substrates, gives rise to the formation of the target compounds in moderate to good yields. ...[more]

PMID: 21915223

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