Cationic gold(I) axially chiral biaryl bisphosphine complex-catalyzed atropselective synthesis of heterobiaryls.

ABSTRACT: It has been established that a cationic gold(I)/(R)-DTBM-Segphos or (R)-BINAP complex catalyzes the atropselective intramolecular hydroarylation of alkynes leading to enantioenriched axially chiral 4-aryl-2-quinolinones and 4-arylcoumarins with up to 61% ee.

SUBMITTER: Shibuya T 

PROVIDER: S-EPMC3170204 | biostudies-literature | 2011

REPOSITORIES: biostudies-literature