Homocoupling of aryl halides in flow: Space integration of lithiation and FeCl(3) promoted homocoupling.

ABSTRACT: The use of FeCl(3) resulted in a fast homocoupling of aryllithiums, and this enabled its integration with the halogen-lithium exchange reaction of aryl halides in a flow microreactor. This system allows the homocoupling of two aryl halides bearing electrophilic functional groups, such as CN and NO(2), in under a minute.

SUBMITTER: Nagaki A 

PROVIDER: S-EPMC3170206 | biostudies-literature | 2011

REPOSITORIES: biostudies-literature