Effects of obstructive sleep apnea and gastroesophageal reflux disease on asthma control in obesity.

ABSTRACT:

Background

Obesity is a risk factor for asthma. Obese asthmatics often have poor asthma control and respond poorly to therapy. It has been suggested that co-morbidities associated with obesity, such as reflux and obstructive sleep apnea, could be important factors contributing to poor asthma control in obese patients.

Objectives

The purpose of this study was to determine if (1) reflux and/or (2) symptoms of sleep apnea contribute to poor asthma control in obesity.

Methods

We studied asthmatic subjects participating in a trial of reflux treatment. Participants underwent baseline evaluation of asthma symptoms and lung function. Overall 304 participants underwent esophageal pH probe testing; 246 participants were evaluated for obstructive sleep apnea symptoms.

Results

SUBMITTER: Dixon AE 

PROVIDER: S-EPMC3171804 | biostudies-literature | 2011 Sep

REPOSITORIES: biostudies-literature