Incidence of epilepsy: a systematic review and meta-analysis.

ABSTRACT:

Objective

To estimate the pooled incidence of epilepsy from published studies and investigate sources of heterogeneity in the estimates.

Methods

We searched online databases for incidence studies and used meta-analytic methods to analyze the data.

Results

Thirty-three articles met the entry criteria. The median incidence of epilepsy was 50.4/100,000/year (interquartile range [IQR] 33.6-75.6), while it was 45.0 (IQR 30.3-66.7) for high-income countries and 81.7 (IQR 28.0-239.5) for low- and middle-income countries. Population-based studies had higher incidence estimates than hospital-based studies (p = 0.02) while retrospective study design was associated with lower estimates than prospective studies (p = 0.04).

Conclusion

We provide data that could potentially

SUBMITTER: Ngugi AK 

PROVIDER: S-EPMC3171955 | biostudies-literature | 2011 Sep

REPOSITORIES: biostudies-literature