The Arabidopsis det3 mutant reveals a central role for the vacuolar H(+)-ATPase in plant growth and development.

ABSTRACT: In all multicellular organisms growth and morphogenesis must be coordinated, but for higher plants, this is of particular importance because the timing of organogenesis is not fixed but occurs in response to environmental constraints. One particularly dramatic developmental juncture is the response of dicotyledonous seedlings to light. The det3 mutant of Arabidopsis develops morphologically as a light-grown plant even when it is grown in the dark. In addition, it shows organ-specific defects in cell elongation and has a reduced response to brassinosteroids (BRs). We have isolated the DET3 gene by positional cloning and provide functional and biochemical evidence that it encodes subunit C of the vacuolar H(+)-ATPase (V-ATPase). We show that the hypocotyl elongation defect in the det3 mutant

SUBMITTER: Schumacher K 

PROVIDER: S-EPMC317205 | biostudies-literature | 1999 Dec

REPOSITORIES: biostudies-literature