Selenium status and blood lipids: the cardiovascular risk in Young Finns study.

ABSTRACT:

Background

Concern has been recently raised about possible adverse cardio-metabolic effects of high selenium status, such as increased risks of diabetes and hyperlipidaemia. However, most of the evidence comes from selenium-replete populations such as that of the United States.

Objectives

To examine cross-sectional and longitudinal associations of serum selenium with cardiovascular risk factors in Finland where selenium levels were amongst the lowest in the world until the early 1980s before the implementation of a nationwide selenium fertilization programme.

Methods

Serum selenium was measured in 1235 young Finns aged 3-18 years at baseline in 1980 (prefertilization) and in a subgroup (N = 262) at the 6-year follow-up (1986, postfertilization). During the 27-year fol

SUBMITTER: Stranges S 

PROVIDER: S-EPMC3172343 | biostudies-literature | 2011 Nov

REPOSITORIES: biostudies-literature