The WD-repeat protein superfamily in Arabidopsis: conservation and divergence in structure and function.

ABSTRACT:

Background

The WD motif (also known as the Trp-Asp or WD40 motif) is found in a multitude of eukaryotic proteins involved in a variety of cellular processes. Where studied, repeated WD motifs act as a site for protein-protein interaction, and proteins containing WD repeats (WDRs) are known to serve as platforms for the assembly of protein complexes or mediators of transient interplay among other proteins. In the model plant Arabidopsis thaliana, members of this superfamily are increasingly being recognized as key regulators of plant-specific developmental events.

Results

We analyzed the predicted complement of WDR proteins from Arabidopsis, and compared this to those from budding yeast, fruit fly and human to illustrate both conservation and divergence in structure and funct

SUBMITTER: van Nocker S 

PROVIDER: S-EPMC317288 | biostudies-literature | 2003 Dec

REPOSITORIES: biostudies-literature