A multi-organ transcriptome resource for the Burmese Python (Python molurus bivittatus).

ABSTRACT:

Background

Snakes provide a unique vertebrate system for studying a diversity of extreme adaptations, including those related to development, metabolism, physiology, and venom. Despite their importance as research models, genomic resources for snakes are few. Among snakes, the Burmese python is the premier model for studying extremes of metabolic fluctuation and physiological remodelling. In this species, the consumption of large infrequent meals can induce a 40-fold increase in metabolic rate and more than a doubling in size of some organs. To provide a foundation for research utilizing the python, our aim was to assemble and annotate a transcriptome reference from the heart and liver. To accomplish this aim, we used the 454-FLX sequencing platform to collect sequence data from mu

SUBMITTER: Castoe TA 

PROVIDER: S-EPMC3173347 | biostudies-literature | 2011 Aug

REPOSITORIES: biostudies-literature