Differential transcriptomic profiles effected by oil palm phenolics indicate novel health outcomes.

ABSTRACT:

Background

Plant phenolics are important nutritional antioxidants which could aid in overcoming chronic diseases such as cardiovascular disease and cancer, two leading causes of death in the world. The oil palm (Elaeis guineensis) is a rich source of water-soluble phenolics which have high antioxidant activities. This study aimed to identify the in vivo effects and molecular mechanisms involved in the biological activities of oil palm phenolics (OPP) during healthy states via microarray gene expression profiling, using mice supplemented with a normal diet as biological models.

Results

Having confirmed via histology, haematology and clinical biochemistry analyses that OPP is not toxic to mice, we further explored the gene expression changes caused by OPP through statistical a

SUBMITTER: Leow SS 

PROVIDER: S-EPMC3175228 | biostudies-literature | 2011 Aug

REPOSITORIES: biostudies-literature