Incidence of breast cancer in the United States: current and future trends.

ABSTRACT:

Background

The incidence of breast cancer increased in the United States until circa 2000 then decreased, mostly among women with estrogen receptor (ER)-positive cancers. Time trends provide important clues for cancer etiology and prevention; however, the observed trends of ER-positive and ER-negative breast cancers can be biased by missing ER data.

Methods

We developed a simple imputation method to correct invasive female breast cancer incidence for missing or unknown ER expression, using nationally representative data from the National Cancer Institute's Surveillance, Epidemiology, and End Results Program during 1980-2008, including 588,720 invasive female breast cancer patients with 471,336,233 woman-years of follow-up. Corrected rates of ER-positive and ER-negative breas

SUBMITTER: Anderson WF 

PROVIDER: S-EPMC3176776 | biostudies-literature | 2011 Sep

REPOSITORIES: biostudies-literature