A new multi-gram synthetic route to labeling precursors for the D(2/3) PET agent 18F-fallypride.

ABSTRACT: This Letter describes a new multi-gram synthetic protocol for the preparation of the classic tosylate labeling precursor for the D(2/3) PET agent [(18)F]fallypride. In the course of our studies, we also discovered two novel labeling precusors, the previously undescribed mesylate and chloro congeners of fallypride.

SUBMITTER: Kim K 

PROVIDER: S-EPMC3177602 | biostudies-literature | 2008 Aug

REPOSITORIES: biostudies-literature