Direct measurements of DNA-mediated colloidal interactions and their quantitative modeling.

ABSTRACT: DNA bridging can be used to induce specific attractions between small particles, providing a highly versatile approach to creating unique particle-based materials having a variety of periodic structures. Surprisingly, given the fact that the thermodynamics of DNA strands in solution are completely understood, existing models for DNA-induced particle interactions are typically in error by more than an order of magnitude in strength and a factor of two in their temperature dependence. This discrepancy has stymied efforts to design the complex temperature, sequence and time-dependent interactions needed for the most interesting applications, such as materials having highly complex or multicomponent microstructures or the ability to reconfigure or self-replicate. Here we report high-spatial re

SUBMITTER: Rogers WB 

PROVIDER: S-EPMC3179119 | biostudies-literature | 2011 Sep

REPOSITORIES: biostudies-literature