Surgery versus watchful waiting in patients with craniofacial fibrous dysplasia--a meta-analysis.

ABSTRACT:

Background

Fibrous dysplasia (FD) is a benign bone tumor which most commonly involves the craniofacial skeleton. The most devastating consequence of craniofacial FD (CFD) is loss of vision due to optic nerve compression (ONC). Radiological evidence of ONC is common, however the management of this condition is not well established. Our objective was to compare the long-term outcome of patients with optic nerve compression (ONC) due to craniofacial fibrous dysplasia (CFD) who either underwent surgery or were managed expectantly.

Methodology/principal findings

We performed a meta-analysis of 27 studies along with analysis of the records of a cohort of patients enrolled in National Institutes of Health (NIH) protocol 98-D-0145, entitled Screening and Natural History of Fibrous D

SUBMITTER: Amit M 

PROVIDER: S-EPMC3179490 | biostudies-literature | 2011

REPOSITORIES: biostudies-literature