A novel amniote model of epimorphic regeneration: the leopard gecko, Eublepharis macularius.

ABSTRACT:

Background

Epimorphic regeneration results in the restoration of lost tissues and structures from an aggregation of proliferating cells known as a blastema. Among amniotes the most striking example of epimorphic regeneration comes from tail regenerating lizards. Although tail regeneration is often studied in the context of ecological costs and benefits, details of the sequence of tissue-level events are lacking. Here we investigate the anatomical and histological events that characterize tail regeneration in the leopard gecko, Eublepharis macularius.

Results

Tail structure and tissue composition were examined at multiple days following tail loss, revealing a conserved pattern of regeneration. Removal of the tail results in a consistent series of morphological and histologica

SUBMITTER: McLean KE 

PROVIDER: S-EPMC3180301 | biostudies-literature | 2011 Aug

REPOSITORIES: biostudies-literature