A systems approach to identifying correlated gene targets for the loss of colour pigmentation in plants.

ABSTRACT:

Background

The numerous diverse metabolic pathways by which plant compounds can be produced make it difficult to predict how colour pigmentation is lost for different tissues and plants. This study employs mathematical and in silico methods to identify correlated gene targets for the loss of colour pigmentation in plants from a whole cell perspective based on the full metabolic network of Arabidopsis. This involves extracting a self-contained flavonoid subnetwork from the AraCyc database and calculating feasible metabolic routes or elementary modes (EMs) for it. Those EMs leading to anthocyanin compounds are taken to constitute the anthocyanin biosynthetic pathway (ABP) and their interplay with the rest of the EMs is used to study the minimal cut sets (MCSs), which are different co

SUBMITTER: Clark ST 

PROVIDER: S-EPMC3180701 | biostudies-literature | 2011 Aug

REPOSITORIES: biostudies-literature