Structure-Composition-Property Relationships in Polymeric Amorphous Calcium Phosphate-Based Dental Composites.

ABSTRACT: Our studies of amorphous calcium phosphate (ACP)-based materials over the last decade have yielded bioactive polymeric composites capable of protecting teeth from demineralization or even regenerating lost tooth mineral. The anti-cariogenic/re-mineralizing potential of these ACP composites originates from their propensity, when exposed to the oral environment, to release in a sustained manner sufficient levels of mineral-forming calcium and phosphate ions to promote formation of stable apatitic tooth mineral. However, the less than optimal ACP filler/resin matrix cohesion, excessive polymerization shrinkage and water sorption of these experimental materials can adversely affect their physicochemical and mechanical properties, and, ultimately, limit their lifespan. This study demonstrates t

SUBMITTER: O'Donnell JN 

PROVIDER: S-EPMC3182464 | biostudies-literature | 2009

REPOSITORIES: biostudies-literature