HIV and concurrent sexual partnerships: modelling the role of coital dilution.

ABSTRACT:

Background

The concurrency hypothesis asserts that high prevalence of overlapping sexual partnerships explains extraordinarily high HIV levels in sub-Saharan Africa. Earlier simulation models show that the network effect of concurrency can increase HIV incidence, but those models do not account for the coital dilution effect (non-primary partnerships have lower coital frequency than primary partnerships).

Methods

We modify the model of Eaton et al (AIDS and Behavior, September 2010) to incorporate coital dilution by assigning lower coital frequencies to non-primary partnerships. We parameterize coital dilution based on the empirical work of Morris et al (PLoS ONE, December 2010) and others. Following Eaton et al, we simulate the daily transmission of HIV over 250 years for 1

SUBMITTER: Sawers L 

PROVIDER: S-EPMC3182950 | biostudies-literature | 2011 Sep

REPOSITORIES: biostudies-literature