Genomic analysis of QTLs and genes altering natural variation in stochastic noise.

ABSTRACT: Quantitative genetic analysis has long been used to study how natural variation of genotype can influence an organism's phenotype. While most studies have focused on genetic determinants of phenotypic average, it is rapidly becoming understood that stochastic noise is genetically determined. However, it is not known how many traits display genetic control of stochastic noise nor how broadly these stochastic loci are distributed within the genome. Understanding these questions is critical to our understanding of quantitative traits and how they relate to the underlying causal loci, especially since stochastic noise may be directly influenced by underlying changes in the wiring of regulatory networks. We identified QTLs controlling natural variation in stochastic noise of glucosinolates, pla

SUBMITTER: Jimenez-Gomez JM 

PROVIDER: S-EPMC3183082 | biostudies-literature | 2011 Sep

REPOSITORIES: biostudies-literature