Cd(II) and Pb(II) complexes of the polyether ionophorous antibiotic salinomycin.

ABSTRACT:

Background

The natural polyether ionophorous antibiotics are used for the treatment of coccidiosis in poultry and ruminants. They are effective agents against infections caused by Gram-positive microorganisms. On the other hand, it was found that some of these compounds selectively bind lead(II) ions in in vivo experiments, despite so far no Pb(II)-containing compounds of defined composition have been isolated and characterized. To assess the potential of polyether ionophores as possible antidotes in the agriculture, a detailed study on their in vitro complexation with toxic metal ions is required. In the present paper we report for the first time the preparation and the structure elucidation of salinomycin complexes with ions of cadmium(II) and lead(II).

Results

New metal(I

SUBMITTER: Ivanova J 

PROVIDER: S-EPMC3184049 | biostudies-literature | 2011 Sep

REPOSITORIES: biostudies-literature