"Glucose and ethanol-dependent transcriptional regulation of the astaxanthin biosynthesis pathway in Xanthophyllomyces dendrorhous".

ABSTRACT:

Background

The yeast Xanthophyllomyces dendrorhous is one of the most promising and economically attractive natural sources of astaxanthin. The biosynthesis of this valuable carotenoid is a complex process for which the regulatory mechanisms remain mostly unknown. Several studies have shown a strong correlation between the carbon source present in the medium and the amount of pigments synthesized. Carotenoid production is especially low when high glucose concentrations are used in the medium, while a significant increase is observed with non-fermentable carbon sources. However, the molecular basis of this phenomenon has not been established.

Results

In this work, we showed that glucose caused transcriptional repression of the three genes involved in the synthesis of astaxant

SUBMITTER: Marcoleta A 

PROVIDER: S-EPMC3184065 | biostudies-literature | 2011 Aug

REPOSITORIES: biostudies-literature