Course of subthreshold bipolar disorder in youth: diagnostic progression from bipolar disorder not otherwise specified.

ABSTRACT:

Objective

To determine the rate of diagnostic conversion from an operationalized diagnosis of bipolar disorder not otherwise specified (BP-NOS) to bipolar I disorder (BP-I) or bipolar II disorder (BP-II) in youth over prospective follow-up and to identify factors associated with conversion.

Method

Subjects were 140 children and adolescents recruited from clinical referrals or advertisement who met operationalized criteria for BP-NOS at intake and participated in at least one follow-up evaluation (91% of initial cohort). Diagnoses were assessed at follow-up interviews using the Longitudinal Interval Follow-Up Evaluation. The mean duration of follow-up was 5 years and the mean interval between assessments was 8.2 months.

Results

Diagnostic conversion to BP-I or BP-II oc

SUBMITTER: Axelson DA 

PROVIDER: S-EPMC3185249 | biostudies-literature | 2011 Oct

REPOSITORIES: biostudies-literature