Suitability of PSA-detected localised prostate cancers for focal therapy: experience from the ProtecT study.

ABSTRACT:

Background

Contemporary screening for prostate cancer frequently identifies small volume, low-grade lesions. Some clinicians have advocated focal prostatic ablation as an alternative to more aggressive interventions to manage these lesions. To identify which patients might benefit from focal ablative techniques, we analysed the surgical specimens of a large sample of population-detected men undergoing radical prostatectomy as part of a randomised clinical trial.

Methods

Surgical specimens from 525 men who underwent prostatectomy within the ProtecT study were analysed to determine tumour volume, location and grade. These findings were compared with information available in the biopsy specimen to examine whether focal therapy could be provided appropriately.

Results

Sol

SUBMITTER: Catto JW 

PROVIDER: S-EPMC3185935 | biostudies-literature | 2011 Sep

REPOSITORIES: biostudies-literature