Cardiac magnetic resonance assessment of left ventricular mass in autosomal dominant polycystic kidney disease.

ABSTRACT:

Background and objectives

Autosomal dominant polycystic kidney disease (ADPKD) is associated with a substantial cardiovascular disease burden including early onset hypertension, intracranial aneurysms, and left ventricular hypertrophy (LVH). A 41% prevalence of LVH has been reported in ADPKD, using echocardiographic assessment of LV mass (LVM). The HALT PKD study was designed to assess the effect of intensive angiotensin blockade on progression of total kidney volume and LVM. Measurements of LVM were performed using cardiac magnetic resonance (MR).

Design, setting, participants, & measurements

Five hundred forty-three hypertensive patients with GFR >60 ml/min per 1.73 m(2) underwent MR assessment of LVM at baseline. LVM was adjusted for body surface area and expressed as LVM

SUBMITTER: Perrone RD 

PROVIDER: S-EPMC3186455 | biostudies-literature | 2011 Oct

REPOSITORIES: biostudies-literature