A blueprint of ectoine metabolism from the genome of the industrial producer Halomonas elongata DSM 2581 T.

ABSTRACT: The halophilic γ-proteobacterium Halomonas elongata DSM 2581(T) thrives at high salinity by synthesizing and accumulating the compatible solute ectoine. Ectoine levels are highly regulated according to external salt levels but the overall picture of its metabolism and control is not well understood. Apart from its critical role in cell adaptation to halophilic environments, ectoine can be used as a stabilizer for enzymes and as a cell protectant in skin and health care applications and is thus produced annually on a scale of tons in an industrial process using H. elongata as producer strain. This paper presents the complete genome sequence of H. elongata (4,061,296 bp) and includes experiments and analysis identifying and characterizing the entire ectoine metabolism, including a newly disc

SUBMITTER: Schwibbert K 

PROVIDER: S-EPMC3187862 | biostudies-literature | 2011 Aug

REPOSITORIES: biostudies-literature