Metabolic network modularity in archaea depends on growth conditions.

ABSTRACT: Network modularity is an important structural feature in metabolic networks. A previous study suggested that the variability in natural habitat promotes metabolic network modularity in bacteria. However, since many factors influence the structure of the metabolic network, this phenomenon might be limited and there may be other explanations for the change in metabolic network modularity. Therefore, we focus on archaea because they belong to another domain of prokaryotes and show variability in growth conditions (e.g., trophic requirement and optimal growth temperature), but not in habitats because of their specialized growth conditions (e.g., high growth temperature). The relationship between biological features and metabolic network modularity is examined in detail. We first show the absen

SUBMITTER: Takemoto K 

PROVIDER: S-EPMC3188556 | biostudies-literature | 2011

REPOSITORIES: biostudies-literature