Treatment of advanced hepatocellular carcinoma with very low levels of amplitude-modulated electromagnetic fields.

ABSTRACT:

Background

Therapeutic options for patients with advanced hepatocellular carcinoma (HCC) are limited. There is emerging evidence that the growth of cancer cells may be altered by very low levels of electromagnetic fields modulated at specific frequencies.

Methods

A single-group, open-label, phase I/II study was performed to assess the safety and effectiveness of the intrabuccal administration of very low levels of electromagnetic fields amplitude modulated at HCC-specific frequencies in 41 patients with advanced HCC and limited therapeutic options. Three-daily 60-min outpatient treatments were administered until disease progression or death. Imaging studies were performed every 8 weeks. The primary efficacy end point was progression-free survival 6 months. Secondary efficac

SUBMITTER: Costa FP 

PROVIDER: S-EPMC3188936 | biostudies-literature | 2011 Aug

REPOSITORIES: biostudies-literature