Long-term use of a nasal expiratory positive airway pressure (EPAP) device as a treatment for obstructive sleep apnea (OSA).

ABSTRACT:

Study objectives

Evaluate the long-term durability of treatment response and safety of a nasal expiratory positive airway pressure (EPAP) device used to treat obstructive sleep apnea (OSA).

Design

A prospective, multicenter, single-arm, open-label extension to a 3-month EPAP vs sham randomized clinical trial

Setting

13 sites including both academic and private sleep disorder centers

Patients

OSA patients in the EPAP arm of the EPAP vs sham randomized study who used the EPAP device ≥ 4 h per night, ≥ 5 nights per week on average during months 1 and 2 of the 3-month trial and had ≥ 50% reduction in AHI or AHI reduction to < 10 documented by polysomnography, comparing the 3-month device-on PSG to the week-one device-off PSG.

Interventions

Treatment with a n

SUBMITTER: Kryger MH 

PROVIDER: S-EPMC3190843 | biostudies-literature | 2011 Oct

REPOSITORIES: biostudies-literature