Re-emergence of Crimean-Congo hemorrhagic fever virus in Central Africa.

ABSTRACT:

Background

Crimean-Congo hemorrhagic fever (CCHF) is a severe tick-borne disease well recognized through Europe and Asia where diagnostic tests and medical surveillance are available. However, it is largely neglected in Africa, especially in the tropical rainforest of Central Africa where only sporadic human cases have been reported and date back to more than 30 years. We describe here an isolated human case that occurred in the Democratic Republic of the Congo in 2008 and performed phylogenetic analysis to investigate whether it resulted from a regional re-emergence or from the introduction of a novel virus in the area.

Methods and findings

Near complete segment S and partial segment M sequences were characterized. Bayesian phylogenetic analysis and datation were performed

SUBMITTER: Grard G 

PROVIDER: S-EPMC3191127 | biostudies-literature | 2011 Oct

REPOSITORIES: biostudies-literature