Identical functional organization of nonpolytene and polytene chromosomes in Drosophila melanogaster.

ABSTRACT: Salivary gland polytene chromosomes demonstrate banding pattern, genetic meaning of which is an enigma for decades. Till now it is not known how to mark the band/interband borders on physical map of DNA and structures of polytene chromosomes are not characterized in molecular and genetic terms. It is not known either similar banding pattern exists in chromosomes of regular diploid mitotically dividing nonpolytene cells. Using the newly developed approach permitting to identify the interband material and localization data of interband-specific proteins from modENCODE and other genome-wide projects, we identify physical limits of bands and interbands in small cytological region 9F13-10B3 of the X chromosome in D. melanogaster, as well as characterize their general molecular features. Our res

SUBMITTER: Vatolina TY 

PROVIDER: S-EPMC3191165 | biostudies-literature | 2011

REPOSITORIES: biostudies-literature