The annotation of the asparagine N-linked glycosylation pathway in the Reactome database.

ABSTRACT: Asparagine N-linked glycosylation is one of the most important forms of protein post-translational modification in eukaryotes and is one of the first metabolic pathways described at a biochemical level. Here, we report a new annotation of this pathway for the Human species, published after passing a peer-review process in Reactome. The new annotation presented here offers a high level of detail and provides references and descriptions for each reaction, along with integration with GeneOntology and other databases. The open-source approach of Reactome toward annotation encourages feedback from its users, making it easier to keep the annotation of this pathway updated with future knowledge. Reactome's web interface allows easy navigation between steps involved in the pathway to compare it wi

SUBMITTER: Dall'Olio GM 

PROVIDER: S-EPMC3191915 | biostudies-literature | 2011 Nov

REPOSITORIES: biostudies-literature