Impact of antimicrobial stewardship programme changes on unnecessary double anaerobic coverage therapy.

ABSTRACT:

Background

Concern has been raised over the practice of unnecessary double anaerobic coverage therapy (DACT) in the hospital setting. However, the incidence of and risk factors for unnecessary DACT are not well studied. On 8 September 2008, the antimicrobial stewardship programme (ASP) at our institution was modified such that several antibiotics, including ampicillin/sulbactam and metronidazole, no longer required pre-approval. We anticipated that this change would increase both unnecessary DACT and target antibiotic consumption.

Methods

A nested case-control study was conducted to determine the cumulative incidence of and risk factors for unnecessary DACT. Cases were subjects who received unnecessary DACT while controls were subjects who did not receive DACT or who receive

SUBMITTER: Rattanaumpawan P 

PROVIDER: S-EPMC3191943 | biostudies-literature | 2011 Nov

REPOSITORIES: biostudies-literature