Viral replication, persistence in water and genetic characterization of two influenza A viruses isolated from surface lake water.

ABSTRACT: Water-borne transmission has been suggested as an important transmission mechanism for Influenza A (IA) viruses in wild duck populations; however, relatively few studies have attempted to detect IA viruses from aquatic habitats. Water-isolated viruses have rarely been genetically characterized and evaluation for persistence in water and infectivity in natural hosts has never been documented. In this study, we focused on two IA viruses (H3N8 and H4N6 subtypes) isolated from surface lake water in Minnesota, USA. We investigated the relative prevalence of the two virus subtypes in wild duck populations at the sampling site and their genetic relatedness to IA viruses isolated in wild waterbirds in North America. Viral persistence under different laboratory conditions (temperature and pH) and r

SUBMITTER: Lebarbenchon C 

PROVIDER: S-EPMC3197669 | biostudies-literature | 2011

REPOSITORIES: biostudies-literature