Similar VLDL-TG storage in visceral and subcutaneous fat in obese and lean women.

ABSTRACT:

Objective

Excess visceral fat accumulation is associated with the metabolic disturbances of obesity. Differential lipid redistribution through lipoproteins may affect body fat distribution. This is the first study to investigate VLDL-triglyceride (VLDL-TG) storage in visceral fat.

Research design and methods

Nine upper-body obese (UBO; waist circumference >88 cm) and six lean (waist circumference <80 cm) women scheduled for elective tubal ligation surgery were studied. VLDL-TG storage in visceral, upper-body subcutaneous (UBSQ), and lower-body subcutaneous (LBSQ) fat were measured with [9,10-(3)H]-triolein-labeled VLDL.

Results

VLDL-TG storage in visceral fat accounted for only ~0.8% of VLDL-TG turnover in UBO and lean women, respectively. A significantly larger propo

SUBMITTER: Sondergaard E 

PROVIDER: S-EPMC3198059 | biostudies-literature | 2011 Nov

REPOSITORIES: biostudies-literature