Discrimination of benign and malignant breast lesions by using shutter-speed dynamic contrast-enhanced MR imaging.

ABSTRACT:

Purpose

To assess the accuracy of the shutter-speed approach compared with standard approach dynamic contrast material-enhanced magnetic resonance (MR) imaging pharmacokinetic analysis for breast cancer diagnosis.

Materials and methods

This study was approved by the institutional review board and was HIPAA compliant. Informed consent was obtained from 89 high-risk women (age range, 28-83 years) who had 92 suspicious lesions with negative findings at mammography (but visible at MR imaging). Each underwent a research dynamic contrast-enhanced MR imaging examination just prior to a clinical MR imaging-guided interventional procedure. Tumor region of interest (ROI) averaged and (for some) pixel-by-pixel dynamic contrast-enhanced time-course data, together with mean arterial inpu

SUBMITTER: Huang W 

PROVIDER: S-EPMC3198224 | biostudies-literature | 2011 Nov

REPOSITORIES: biostudies-literature