Furan fatty acid as an anti-inflammatory component from the green-lipped mussel Perna canaliculus.

ABSTRACT: A lipid extract of Perna canaliculus (New Zealand green-lipped mussel) has reportedly displayed anti-inflammatory effects in animal models and in human controlled studies. However, the anti-inflammatory lipid components have not been investigated in detail due to the instability of the lipid extract, which has made the identification of the distinct active components a formidable task. Considering the instability of the active component, we carefully fractionated a lipid extract of Perna canaliculus (Lyprinol) and detected furan fatty acids (F-acids). These naturally but rarely detected fatty acids show potent radical-scavenging ability and are essential constituents of plants and algae. Based on these data, it has been proposed that F-acids could be potential antioxidants, which may contr

SUBMITTER: Wakimoto T 

PROVIDER: S-EPMC3198329 | biostudies-literature | 2011 Oct

REPOSITORIES: biostudies-literature