The impact of osteitis on disease severity measures and quality of life outcomes in chronic rhinosinusitis.

ABSTRACT:

Background

The significance of osteitis in the management of recalcitrant chronic rhinosinusitis (CRS) has yet to be clearly understood and clinical outcomes data for these patients is lacking. Osteitis has been characterized by inflammatory infiltrate, osteoneogenesis, and bony sclerosis with remodeling. In this study we sought to determine if osteitis negatively impacts quality-of-life (QOL) or clinical outcomes following endoscopic sinus surgery (ESS).

Methods

A total of 190 adult patients with CRS were prospectively enrolled.Osteitis was characterized by quantifiable bony thickening on sinus computed tomography (CT). Baseline measures and postoperative outcomes were evaluated using endoscopy exam, olfactory testing, and 2 validated disease-specific QOL surveys: the Chron

SUBMITTER: Bhandarkar ND 

PROVIDER: S-EPMC3198819 | biostudies-literature | 2011 Sep-Oct

REPOSITORIES: biostudies-literature