Does metastasectomy improve survival in patients with Stage IV melanoma? A cancer registry analysis of outcomes.

ABSTRACT:

Introduction

Patients with Stage IV melanoma have limited therapeutic options with few long-term survivors. Our goal was to study the impact of metastasectomy on survival in these patients.

Methods

Patients with Stage IV melanoma were identified from the Surveillance, Epidemiology, and End Results (SEER) database (1988-2006). Those who had metastasectomy performed were compared with patients that did not.

Results

The median age of the study population (n = 4,229) was 63 years and median survival was 7 months. Patients who underwent metastasectomy (33.6%) had an improved median and 5-year overall survival as compared to patients who did not; 12 months versus 5 months and 16% versus 7% (P < 0.001). In patients with M1a disease (n = 1,994), this improvement of survival f

SUBMITTER: Wasif N 

PROVIDER: S-EPMC3199373 | biostudies-literature | 2011 Aug

REPOSITORIES: biostudies-literature