The logopenic variant of primary progressive aphasia.

ABSTRACT:

Purpose of review

The aim is to explore the evolution of the logopenic variant of primary progressive aphasia as a distinct clinical entity and to outline recent advances that have clarified its clinical characteristics, neural underpinnings, and potential genetic and pathological bases. This is particularly relevant as researchers attempt to identify clinico-pathological relationships in subtypes of primary progressive aphasia in hopes of utilizing language phenotype as a marker of underlying disease.

Recent findings

Recent work has served to refine and expand upon the clinical phenotype of the logopenic variant. Logopenic patients show a unique pattern of spared and impaired language processes that reliably distinguish this syndrome from other variants of progressive aphas

SUBMITTER: Henry ML 

PROVIDER: S-EPMC3201824 | biostudies-literature | 2010 Dec

REPOSITORIES: biostudies-literature