Risk of venous thromboembolism from use of oral contraceptives containing different progestogens and oestrogen doses: Danish cohort study, 2001-9.

ABSTRACT:

Objective

To assess the risk of venous thromboembolism from use of combined oral contraceptives according to progestogen type and oestrogen dose.

Design

National historical registry based cohort study.

Setting

Four registries in Denmark.

Participants

Non-pregnant Danish women aged 15-49 with no history of thrombotic disease and followed from January 2001 to December 2009.

Main outcome measures

Relative and absolute risks of first time venous thromboembolism.

Results

Within 8,010,290 women years of observation, 4307 first ever venous thromboembolic events were recorded and 4246 included, among which 2847 (67%) events were confirmed as certain. Compared with non-users of hormonal contraception, the relative risk of confirmed venous thromboembolism i

SUBMITTER: Lidegaard O 

PROVIDER: S-EPMC3202015 | biostudies-literature | 2011 Oct

REPOSITORIES: biostudies-literature