Common carotid artery intima-media thickness progression as a predictor of stroke in multi-ethnic study of atherosclerosis.

ABSTRACT:

Background and purpose

Carotid artery intima-media thickness (IMT) is a marker of cardiovascular disease associated with incident stroke. We studied whether IMT rate of change is associated with stroke.

Methods

We studied 5028 participants of the Multi-Ethnic Study of Atherosclerosis (MESA) comprising white, Chinese, Hispanic, and black participants free of cardiovascular disease. In this MESA IMT progression study, IMT rate of change (mm/year) was the difference in right common carotid artery far wall IMT (mm) divided by the interval between 2 ultrasound examinations (median interval, 32 months). Common carotid artery IMT was measured in a region free of plaque. Cardiovascular risk factors and baseline IMT were determined when IMT rate of change was measured. Multivariable

SUBMITTER: Polak JF 

PROVIDER: S-EPMC3202068 | biostudies-literature | 2011 Nov

REPOSITORIES: biostudies-literature