An exploration of subgroups of mild cognitive impairment based on cognitive, neuropsychiatric and functional features: analysis of data from the National Alzheimer's Coordinating Center.

ABSTRACT:

Objectives

To empirically expand the existing subtypes of mild cognitive impairment (MCI) by incorporating information on neuropsychiatric and functional features, and to assess whether cerebrovascular disease (CVD) risk factors are associated with any of these subgroups.

Design

Latent class analysis using 1,655 patients with MCI.

Setting

Participants in the Uniform Data Set (UDS) from 29 National Institutes of Health-supported Alzheimer's Disease Centers.

Participants

Patients with a consensus diagnosis of MCI from each center and with a Mini-Mental State Examination score of 22 or greater.

Measurements

UDS cognitive battery, Neuropsychiatric Inventory Questionnaire, and Functional Assessment Questionnaire administered at initial visit.

Results

S

SUBMITTER: Hanfelt JJ 

PROVIDER: S-EPMC3202691 | biostudies-literature | 2011 Nov

REPOSITORIES: biostudies-literature