Association of oncogenic and nononcogenic human papillomavirus with HIV incidence.

ABSTRACT:

Objective

Little is known about the interaction between human papillomavirus (HPV) and HIV. This study aimed to explore the association of oncogenic (high risk) and nononcogenic (low risk) HPV with HIV incidence.

Methods

We used 1683 urethral swabs collected at the last follow-up visit of a male circumcision trial conducted in Orange Farm (South Africa). Swabs analyses and HPV genotyping were performed by polymerase chain reaction. We estimated HIV adjusted incidence rate ratios (aIRRs) and 95% confidence intervals (CIs) using survival analysis. Background characteristics, male circumcision status, sexual behavior, HPV status, and other sexually transmitted infections were used as covariates.

Results

The prevalence of HR and LR HPV was 14.0% (95% CI: 12.4 to 15.7) and

SUBMITTER: Auvert B 

PROVIDER: S-EPMC3203884 | biostudies-literature | 2010 Jan

REPOSITORIES: biostudies-literature