Asymmetry, sex differences and age-related changes in the white matter in the healthy elderly: a tract-based study.

ABSTRACT:

Background

Hemispherical asymmetry, sex differences and age-related changes have been reported for the human brain. Meanwhile it was still unclear the presence of the asymmetry or sex differences in the human brain occurred whether as a normal development or as consequences of any pathological changes. The aim of this study was to investigate hemispherical asymmetry, sex differences and age-related changes by using a tract-based analysis in the nerve bundles.

Methods

40 healthy elderly subjects underwent magnetic resonance diffusion tensor imaging, and we calculated fractional anisotropy (FA) and apparent diffusion coefficient (ADC) values along the major white matter bundles.

Results

We identified hemispherical asymmetry in the ADC values for the cingulate fasciculus

SUBMITTER: Kitamura S 

PROVIDER: S-EPMC3205060 | biostudies-literature | 2011 Oct

REPOSITORIES: biostudies-literature