IL13 genetic polymorphisms, smoking, and eczema in women: a case-control study in Japan.

ABSTRACT:

Background

Several genetic association studies have examined the relationships between single nucleotide polymorphisms (SNPs) in the IL13 gene and eczema, and have provided contradictory results. We investigated the relationship between the IL13 SNPs rs1800925 and rs20541 and the risk of eczema in Japanese young adult women.

Methods

Included were 188 cases who met the criteria of the International Study of Asthma and Allergies in Childhood (ISAAC) for eczema. Control subjects were 1,082 women without eczema according to the ISAAC criteria, who had not been diagnosed with atopic eczema by a doctor and who had no current asthma as defined by the European Community Respiratory Health Survey criteria. Adjustment was made for age, region of residence, number of children, smoking,

SUBMITTER: Miyake Y 

PROVIDER: S-EPMC3206833 | biostudies-literature | 2011 Oct

REPOSITORIES: biostudies-literature