Transformation of stimulus value signals into motor commands during simple choice.

ABSTRACT: Decision-making can be broken down into several component processes: assigning values to stimuli under consideration, selecting an option by comparing those values, and initiating motor responses to obtain the reward. Although much is known about the neural encoding of stimulus values and motor commands, little is known about the mechanisms through which stimulus values are compared, and the resulting decision is transmitted to motor systems. We investigated this process using human fMRI in a task where choices were indicated using the left or right hand. We found evidence consistent with the hypothesis that value signals are computed in the ventral medial prefrontal cortex, they are passed to regions of dorsomedial prefrontal cortex and intraparietal sulcus, implementing a comparison proc

SUBMITTER: Hare TA 

PROVIDER: S-EPMC3207676 | biostudies-literature | 2011 Nov

REPOSITORIES: biostudies-literature