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The National Emphysema Treatment Trial (NETT) Part II: Lessons learned about lung volume reduction surgery.


ABSTRACT: Substantial information regarding the role of lung volume reduction surgery (LVRS) in severe emphysema emanates from the National Emphysema Treatment Trial (NETT). The NETT was not a crossover trial and therefore was able to examine the effects of optimal medical management and LVRS on short- and long-term survival,as well as lung function, exercise performance, and quality of life.The NETT generated multiple insights into the preoperative, perioperative,and postoperative management of patients undergoing thoracotomy; described pain control techniques that were safe and effective; and emphasized the need to address nonpulmonary issues to optimize surgical outcomes. After the NETT, newer investigation has focused on bronchoscopic endobronchial interventions and other techniques less invasiv

SUBMITTER: Criner GJ 

PROVIDER: S-EPMC3208657 | biostudies-literature | 2011 Oct

REPOSITORIES: biostudies-literature