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Cellular treatments for spinal cord injury: the time is right for clinical trials.


ABSTRACT: More than 1 million people in the United States live with a spinal cord injury (SCI). Despite medical advances, many patients with SCIs still experience substantial neurological disability, with loss of motor, sensory, and autonomic function. Cell therapy is ideally suited to address the multifactorial nature of the secondary events following SCI. Remarkable advances in our understanding of the pathophysiology of SCI, structural and functional magnetic resonance imaging, image-guided micro-neurosurgical techniques, and transplantable cell biology have enabled the use of cell-based regenerative techniques in the clinic. It is important to note that there are more than a dozen recently completed, ongoing, or recruiting cell therapy clinical trials for SCI that reflect the views of many key s

SUBMITTER: Fehlings MG 

PROVIDER: S-EPMC3210356 | biostudies-literature | 2011 Oct

REPOSITORIES: biostudies-literature